Pubications

Stathopoulos C., Kalpaxis D. L., and Drainas D. Partial purification and characterization of RNase Ρ from Dictyostelium discoideum. Eur. J. Biochem. 228: 976-980.

1. Tekos A., Stathopoulos C., and Drainas D. (1998) Bimodal action of the alkaline earth cations on Dictyostelium discoideum ribonuclease Ρ
2. Tekos A., Tsagla A., Stathopoulos C., and Drainas D. (1999) Inhibition Dictyostelium discoideum ribonuclease Ρ activity by aminoglycosides. Nucleic Acids Symp. Series 41: 152-154.
3. Tumbula D., Vothknecht U.C., Kirn H., Ibba M., Min B., Li T., Pelaschier J., Stathopoulos C., Becker H. D. and Söll D. (1999) Archaeal aminoacyl-tRNA synthesis: diversity replaces dogma. Genetics 152: 1269-1276.
4. LiT., GrahamD. E., StathopoulosC.,HaneyP.J., KirnH., VothknechtU. C., KitabatakeM., HongK., EggertssonG., CurnowA.W., LinW., CelicI., WhitmanW. andSöllD. (1999) Cysteinyl-tRNA formation: the last puzzle of aminoacyl-tRNA synthesis. FEBS Letters 462: 302-306. (ΙF: )
5. Papadimou Ε., Monastirli A., Stathopoulos C., Tsambaos D., and Drainas D. (2000) Modulation of ribonuclease Ρ activity by calcipotriol. 267: 1173-1177.
6. Stathopoulos C., Tsagla A., Tekos A., and Drainas D. (2000) Effect of peptidyltransferase inhibitors on ribonuclease Ρ activity from Dictyostelium discoideum. 27: 107-111.
7. TekosA., TsaglaA., StathopoulosC.andDrainasD. (2000) Inhibition of eukaryotic ribonuclease Ρ activity by aminoglycosides. Kinetic studies. FEBS Letters 485: 71-75.
8. Stathopoulos C., Li T., Longman R., Vothknecht U.C., Becker H.D., Ibba M. and Söll D. (2000). One polypeptide with two aminoacyl-tRNA synthetase activities. Science 287: 479-482.
9. Ibba M., Becker H. D., Stathopoulos C., Tumbula D. and Söll D. (2000) The adaptor hypothesis revisited. Trends Biochem. Sci. 25: 311-316.
10. Bunjun S. (*), Stathopoulos C. (*), Graham D., Min B., Kitabatake M., Wang A.L., Wang   C.C., Vivares C.P., Weiss L.M. and Söll D. (2000) A dual-specificity aminoacyl-tRNA synthetase in the deep rooted eukaryote Giardia lamblia.USA 97: 12997-13002. (*)equal contribution.
11. Stathopoulos C., Jacquin-Becker C., Becker H.D., Li T., Ambrogelly A., Longman R. and Söll D. Methanococcus jannaschii Prolyl-Cysteinyl-tRNA synthetase possesses overlapping amino acid binding sites. Biochemistry 40: 46-52.
12. Stathopoulos C., Tekos A., Zarkadis, I. and Drainas D. (2001) Extensive deproteinization of Dictyostelium discoideum RNase Ρ reveals a new catalytic activity. Eur. J. Biochem. 268: 2134-214
13. Ibba M., Stathopoulos C. and Söll D. . Protein Synthesis: 23 Amino acids and counting. Current Biology 11: 563-565.
14. Ruan B., Ahel I., Ambrogelly A., Becker H. D., Bunjun S., Feng L., Tumbula D., Ibba M., Korencic D., Kobayashi H., Jacquin-Becker C., Mejlhede N., Min B., Raczniak G., Rinehart J., Stathopoulos, C., Li T. and Söll. 48: 313-321.
15. StathopoulosC., KimW., LiT., AndersonI., PaliouraS., WhitmanW. andSöllD. Cysteinyl-tRNAsynthetaseisnotessentialfortheviabilitythearcheaonMethanococcusmaripaludis. . USA 98: 14292-14297.
16. FengL., StathopoulosC., AhelI., MitraA., HartschT., TumbulaD. andSöllD. . Aminoacyl-tRNA formation in the hyperthermophile Themus thermophilus. Extremophiles 6: 167-174.
17. Jacquin-Becker C., Ahel I., Ambrogelly A., Ruan B. Söll D. and Stathopoulos C. Cysteinyl-tRNA formation and prolyl-tRNA synthetase FEBS Letters 514: 34-36.
18. Stathopoulos C., Ahel I., Ambrogelly A., Becker H., Bunjun S., Feng L., Herring S., Jacquin-Becker C., Kobayashi H., Korencic D., Krett B., Mejlhede N., Min B., Nakano H., Namgoong S., Polycarpo C., Raczniak G., Rinehart J., Rosas-Sandoval G., Ruan B., Sabina J., Sauerwald A., Toogood H., Tumbula-Hansen D., Ibba M. and Söll D. . Aminoacyl-tRNA synthesis: a post-genome perspective. Cold Spring Harbor Symp. LXVI 175-183.
19. AhelI., StathopoulosC.,AmbrogellyA., SauerwaldA., ToogoodH., HartschT. andSöllD. Cysteineactivationisaninherentpropertyprolyl-tRNAsynthetases. 277: 34743-34748.
20. Ambrogelly A., Ahel I., Polycarpo C., Bunjun-Srihari S., Krett B., Jacquin-Becker C., Kohrer C., Stathopoulos C., RajBhandary U.L. and Söll D. Methanocaldococcus jannaschii prolyl-tRNA synthetase charges tRNA^Pro with cysteine. J. Biol. Chem. 277: 34749-34754.
21. KalavriziotiD., VourekasA., TekosA., StathopoulosC.andDrainasD. KineticsinhibitionribonucleaseP activity bypeptidyl-transferaseinhibitorsMol. 30: 9-15. (ΙF: 2.506)
22. Kamtekar S., Kennedy D.W., Wang J., Stathopoulos C., SöllT.A. (2003) The structural basis of cysteine aminoacylation of tRNA^Pro by prolyl-tRNA synthetases Proc. . USA 100: 1673-1678.
23. Korencic D., Ahel I., Schelert J., Sacher M., Ruan B., Stathopoulos C., Blum P., Ibba, M. and Söll D. A freestanding proofreading domain isrequired for protein synthesis quality control in archaea. .USA 101: 10260-10265.
24. Tekos A. (*), Stathopoulos C. (*), Tsambaos D. and Drainas D. (2004) RNase P: a screening system and molecular target for the development of new drugs. Curr. Med. Chem. 11: 2979-2989. (*) Equal contribution, first co-authors
25. RuanB., BoveeM.L., SacherM., StathopoulosC., PorallaK., FrancklynC.S. andSöllD. (200A unique hydrophobic cluster near the active site contributes to differences of borrelidin inhibition among threonyl-tRNA synthetases. 280: 571-577.
26. Ambrogelly A., Kamtekar S., Stathopoulos C., Kennedy D. and Söll D. Asymmetrical behavior of archaeal proly-tRNA synthetase FEBSLetters 579: 6017-6022.
27. KottaridiBolanaki E., MamurisZ., StathopoulosC.andMarkoulatosP. Molecular phylogeny of VP1, 2A and 2B genes of echovirus isolates: epidemiological linkage and observations on genetic variation 151: 1117-1132.
28. PaximadiE., KarakasiliotisI., MamurisZ., StathopoulosC., KrikelisV. andMarkoulatosP. GenomicanalysisrecombinantSabinclinicalisolatesVirus Genes 32: 203-210. (IF: )
29. Vourekas A., Kalavrizioti D., Stathopoulos C., (*) and Drainas D. Modulation of catalytic RNA biological activity by small molecule effectors. 6: 971-978. (*) corresponding author
30. Kalavrizioti D. Vourekas A., Stamatopoulou, V., Toumpeki C., Giannouli S., Stathopoulos C., (*) and Drainas D. RNA-mediated therapeutics: from gene inactivation to clinical application 6: 1737-1758. (*) corresponding author
31. Bailly M., Giannouli S., Blaise M., Stathopoulos C. (*), Kern D and Becker H. D. A single tRNA base-pair mediates bacterial tRNA-dependent biosynthesis of 34: 6083-6094. (*) correspondingauthor
32. Vourekas A., Kalavrizioti D., Tekos A., Zarkadis I., Stathopoulos C. (*) and Drainas D. A 40.7 kDa Rpp30/Rpp1 homologue is a protein subunit of Dictyostelium discoideum RNase P holoenzyme. Biochimie 89: 301-310. (*) corresponding author
33. Stagos, Spanou, Margariti, Stathopoulos, Mamuris, Kazantzoglou, MagiatisKouretasD. (2007) Cytogeneticeffectsgrapeextracts (Vitisvinifera) andpolyphenolsmitomycinC-inducedSCEsinhumanbloodlymphocytes. J Agric. Food Chem. 55: 5246-5252.
34. Zifa E., Giannouli S., Theotokis P., Stamatis K., Mamuris Z. and Stathopoulos C. (*) Mitochondrial tRNA mutations: functional and clinical perturbations. RNAbiology 4: 38-66. (*) corresponding author
35. Kontou M., Kristo I., Ikonomidis A., Maniatis A., Pournaras S. and Stathopoulos C. (*)Molecular cloning and biochemical characterization of VIM-12, a novel hybrid metallo-β-lactamase from a Klebsiella pneumoniae clinical isolate, reveals atypical substrate specificity. Biochemistry 46: 13170-13178. (*) corresponding author
36. StamatisC., Giannouli, S., Suchentrunk F., Sert H., StathopoulosC. (*)andMamurisZ. RecruitmentmitochondrialtRNAgenesasauxiliary variability markersfor both intra- and inter-species analyses: theparadigmbrownhare (Lepuseuropaeus)Gene 410: 154-164. (*) corresponding author
37. Zifa E., Theotokis P., Kaminari A., Maridaki H., Leze H., Petsiava E., Mamuris Z. and Stathopoulos C. (*) (2008) A novel G3337A mitochondrial ND1 mutation related to cardiomyopathy co-segregates with tRNA^Leu(CUN) A12308G and tRNA^Thr C15946T mutations. Mitochondrion 8: 229-236. (*) corresponding author
38. Ikonomidis A., Michail G., Vasdeki A., Labrou M., Karavasilis V., Stathopoulos C., Maniatis A. and Pournaras S. (2008) In vitro and in vivo evaluation of oxacillin efficiency on mecA-positive oxacillin-susceptible Staphylococcus aureus. Antimicrob. Agents Chem. 52: 3905-3908.
39. Balatsos N. A. A., Anastasakis D. and Stathopoulos C. (*) Inhibition of human poly(A)-specific ribonuclease (PARN) by purine nucleotides: kinetic analysis. J. Enz. Inh. Med. 24: 516-523. (*) corresponding author
40. GiannouliS., KyritsisA., Malissovas N., BeckerH. D. andStathopoulosC. (*)On the role of an unusual tRNA^Gly isoacceptor in Staphylococcus aureus. Biochimie 91: 344-351. (*) corresponding author
41. Papatheodorou L. K., MalizosK. N., Poultisidis L. A., Hantes M. E., GiannouliS., Grafanaki K., Ioannou M. G., Koukoulis G. K., Protopappas V. C., Fotiadis D. I. andStathopoulosC.Ultrasound Med. Biol. 35: 576-584.
42. Balatsos N. A. A., Vlachakis D., Maragozidis P., Manta S., Anastasakis D., Kyritsis A., Vlassi M., Komiotis D. and Stathopoulos C. (*) . Biochemistry 48: 6044-6051. (*) correspondingauthor
43. GiannouliS., LabrouM., KyritsisA., IkonomidisA., PournarasS., StathopoulosC. (*) and Tsakris A. (2010) DetectionmutationsinFemABXproteinfamilyin-susceptible, mecApositiveStaphylococcusaureusclinicalisolatesJ. Antimicrob. 65: 626-633. (*) correspondingauthor
44. Balatsos N. A. A., Vlachakis D., Chatzigeorgiou V., Manta S., Komiotis D., Vlassi M. and Stathopoulos C. (*) (*) correspondingauthor
45. Tsikrikonis G., Maniatis A.N., Labrou M., Ntokou E., Michail G., Daponte A., Stathopoulos C., Tsakris A. and Pournaras S. Differences in biofilm formation and virulence genes between clinical and fecal enterococcal isolates of human and animal origin. Microbial Pathogenesis 52: 336-343.
46. Ntokou E., Stathopoulos C., Kristo I., Dimitroulia E., Labrou M., Makris D., Zakynhtinos E., Tsakris A. and Pournaras S. (2012) Intensive care unit outbreak caused by multiple clones of linezolid-resistant Enterococcus faecalis and Enterococcus faecium in a tertiary hospital. J Antimicrob. Chemoth. 67: 1819-1823.
47. Balatsos N. A. A., Maragozidis P., Anastasakis D. and Stathopoulos C. (*) (2012) Modulation of poly(A)-specific ribonuclease (PARN): current knowledge and perspectives. Current Med. Chem. 19: 4838-4849. (*) corresponding author
48. Vlachakis D., Pavlopoulou A., Tsiliki G., Komiotis D., Stathopoulos C. Balatsos N. and Kossida S. (2012) An intergraded in silico approach to design specific inhibitors targeting human poly(A)-specific ribonuclease. PLoS ONE. 7: 51113.
49. Karoulia Z., Nomikos M., Thanassoulas A., Papadopoulos G., Papadopoulou-Choli D., Nounessis G., Kontou M., Stathopoulos C. (*), and Leonidas D.D. (2013) Studies on the intramolecular interactions between the A1 and A2 domains of the von Willebrand factor. Protein and Peptide Lett. 20: 131-140. (*) corresponding author
50. Pournaras S., Köck R., Mossialos D., Mellmann A., Sakellaris V., Stathopoulos C., Friedrich A. W. and Tsakris A. (2013) Detection of a phylogenetically distinct IMP-type metallo-ß-lactamase, IMP-35, in a CC235 Pseudomonas aeruginosa from the Dutch-German border region (Euregio). J Antimicrob. Chemoth. 68: 1271-1276.
51. Pournaras S., Ntokou E., Zarkotou O., Ranellou K., Themeli-Digalaki K., Stathopoulos C. and Tsakris A. (2013) Emergence of linezolid-dependent Staphylococcus epidermidis bloodstream isolates. Emerging Infect. Dis. 19: 129-132.
52. Saad N. Y., Stamatopoulou V., Drainas D., Stathopoulos C. (*) and Becker H. D. (2013) Τwo-codon T-box riboswitch binding two tRNAs. Proc. Natl. Acad. Sci. USA 110: 12756-12761. (*) corresponding author
53. Pournaras S., Stathopoulos C. and Tsakris A. (2013) Oxacillin-susceptible MRSA: could it become a successful MRSA type? Future Microbiology 8: 1365-1367.
54. Apostolidi M., Vourtsis D. J., Chasapis C. T., Stathopoulos C., Bentrop D. and Spyroulias G. (2012) ¹H, ¹⁵N, ¹³C assignment and secondary structure determination of two domains of La protein from D. discoideum. Biomol. NMR Assign. 8: 47-51.
55. Kokkori S., Apostolidi M., Tsakris A., Pournaras S., Stathopoulos C. (*) and Dinos G. (2014) Linezolid-dependent structure and function adaptation of ribosomes from linezolid-dependent S. epidermidis. J Antimicrob. Chemoth. 58: 4651-4656. (*) corresponding author
56. Argyriou A. I., Chasapis C. T., Apostolidi M., Konstantinidou P., Stathopoulos C., Bentrop D. and Spyroulias G. (2015) Solution NMR assignment and secondary structure determination of RRM2 domain of La protein from a lower eukaryote exhibiting identical structural organization with its human homolog.9: 219-222.
57. Chasapis C. T., Argyriou A. I., Apostolidi M., Konstantinidou P., Bentrop D., Stathopoulos C. and Spyroulias G. (2015) ¹H, ¹³C and ¹⁵N backbone and side-chain resonance assignment of the La-RRM1 module of La protein from Dictyostelium discoideum.9: 303-307.
58. Karavassilis V., Zarkotou O., Panopoulou M., Kachrimanidou M., Digalaki K., Stylianakis A., Gennimata V., Ntokou E., Stathopoulos C., Tsakris A. and Pournaras S. (2015) Wide dissemination of linezolid-resistant Staphylococcus epidermidis in Greece is associated with a linezolid-dependent ST22 clone. J Antimicrob. Chemoth. 70: 1625-1629.
59. Dailiana Z. H., Christou D. C., Grafanaki K., Ioannou M. G., Stathopoulos C., Malizos K. N. and Varitimidis S. (2015) Histological and biochemical evidence related to the collagen quality in torn rotaor cuff tendons. Acta Orthopaedica Belgica In Press.
60. Apostolidi M., Saad N. Y., Drainas D., Pournaras S., Becker H. D. and Stathopoulos C. (*) (2015) A glyS T-box riboswitch with species-specific structural features responding to both proteinogenic and non-proteinogenic tRNA^Gly isoacceptors. RNA 21:1790-1806. (*) corresponding author